If you are experiencing "There is no disk in the drive. Please insert a disk into drive \Device\Harddisk1\DR1." error when starting a program, e.g. chrome.exe or Dropbox.exe, you might want to try the workaround below.
|"There is no disk in the drive. Please insert a disk into drive \Device\Harddisk1\DR1." error.|
Please remember to run the DriveCleanup tool with Administrator privileges.
Microsoft Windows [Version 6.1.7601]Phew! I do have a lot of old USB storage drive in my home Windows 7 computer. O.O
Copyright (c) 2009 Microsoft Corporation. All rights reserved.
Volume in drive C has no label.
Volume Serial Number is XXXX-XXXX
Directory of C:\Users\Leonard\Downloads\drivecleanup
01/03/2012 19:28 <DIR> .
01/03/2012 19:28 <DIR> ..
20/09/2011 18:40 1,618 DriveCleanup.txt
01/03/2012 19:28 <DIR> Win32
01/03/2012 19:28 <DIR> x64
1 File(s) 1,618 bytes
4 Dir(s) 1,652,068,352 bytes free
DriveCleanup V0.8.1 (Win32)
Uninstalls non present USB hubs, USB storage devices and their storage volumes, Disks, CDROMs, Floppies, WPD devices and deletes their registry items
Freeware by Uwe Sieber - www.uwe-sieber.de
removing USB device 'USB\VID_0421&PID_02F4\353781044919304'
removing USB device 'USB\VID_04E8&PID_6860&MI_01\6&1961B21&0&0001'
removing USB device 'USB\VID_0FCE&PID_D044\3578300132302620'
Regkey delete HKLM\System\MountedDevices\\DosDevices\F:
Regkey delete HKLM\System\MountedDevices\\DosDevices\H:
Regkey delete HKLM\System\MountedDevices\\DosDevices\I:
Regkey delete HKLM\System\MountedDevices\\DosDevices\J:
Regkey delete HKCU\Software\Microsoft\Windows\CurrentVersion\Explorer\MountPoints2\H
Regkey delete HKCU\Software\Microsoft\Windows\CurrentVersion\Explorer\MountPoints2\J
Removed 36 USB devices
Removed 2 USB hubs
Removed 40 Disk devices
Removed 7 CDROM devices
Removed 0 Floppy devices
Removed 47 Storage volumes
Removed 35 WPD devices
Removed 56 Keys from registry
Update (19 March 2012, 19:45): It seems that this issue is not resolved completely by cleaning up old USB drivers.
I tried to scan my computer to find anything suspicious. I started a full scan of my compueter using both Microsoft Safety Scanner and F-Secure Online Scanner, which both are free to use. I didn't find anything suspicious on my computer.
Afterward, I need to recall when the symptoms actually start to occur. I recalled that I did a major cleanup on my computer by removing rarely used programs. This step points me to check my %PATH% environment variable. I saw that my %PATH% environment variable has many broken paths included.
C:\Program Files\PC Connectivity Solution\;
C:\Program Files\Common Files\Microsoft Shared\Windows Live;
C:\Program Files\Windows Live\Shared;
By checking and removing the broken paths, as shown above, I did manage to cleanup the %PATH% variable. Thereafter, this issue is resolved completely.
Hope this helps!